SnapGene - Application Software Download Free Mac application software download free Mac SnapGene makes it easy to plan, visualize and document your molecular biology procedures. Whether you're working with In-Fusion Cloning, Gibson Assembly, Restriction Cloning, PCR & Mutagenesis or Agarose Gel Electrophoresis, each procedure is automatically recorded in a graphical history. Ancesstor constructs are embedded in the final file, making it simple to transfer your work to a new lab member. A variety of sequence formats are supported, so you can switch completely to SnapGene or use it alongside legacy software. Sequences and maps can be exported to GenBank, FASTA or a common image format. Use the intuitive pointer interface to simulate and manipulate DNA strands, sequences and proteins. Choose sequence colors, alternate codons, add features and more. Efficient data handling allows the user to scan large DNA sequences with thousands of annotated features at a glance. Easily edit a DNA sequence, using the revolutionary editor that uses rigorous thermodynamics to calculate melting temperatures and duplex alignments. Sequences up to 1 Gb can be analyzed, annotated and displayed with a graphical map or in a numerical list. Annotate features automatically or manually, with a choice of predefined annotations and custom ones that you can create yourself. Identify DNA fragments in a plasmid, a restriction digest or in a simulated agarose gel. The user can even use the application to plan Gateway cloning, with the program selecting appropriate primers for each recombination step. A library of carefully annotated plasmids and guides to popular cloning methods are also included in the package.